Aspartate Semialdehyde Dehydrogenase

Aspartate semialdehyde dehydrogenase is an enzyme in the conversion of aspartate to homoserine (see here) in the pathway leading to biosynthesis of threonine, isoleucine, and methionine. It catalyzes the reaction that follows:

> -Aspartyl Phosphate + NADPH + H+ <=> Aspartic Semialdehyde + NADP+ + Pi

See also: Metabolism of Serine, Glycine, and Threonine, Metabolism of Valine, Leucine, Isoleucine, and Lysine, Metabolism of Sulfur-Containing Amino Acids