CDP-Diacylglycerol

CDP-diacylglycerol is an important intermediate in biosynthesis of the glycerophospholipids (see Figures 19.2, 19.4, 19.8), leading to synthesis of phosphatidylserine, phosphatidylethanolamine, phosphatidylglycerol, cardiolipin, phosphatidylinositol, and phosphatidylcholine.

CDP-diacylglycerol is made by combining phosphatidic acid and CTP (Figure 19.3). In each of the glycerophospholipid reaction pathways from CDP-diacylglycerol, CMP is split from the molecule in order to put on the serine, ethanolamine, glycerol, or inositol moieties.

See also: Glycerophospholipid Pathway, Glycerophospholipid Metabolism in Eukaryotes, Glycerophospholipid Biosynthesis in Bacteria, Glycerophospholipids

INTERNET LINKS

> 1. Glycerolipid Metabolism

> 2. Phospholipid Catabolism