Glutaredoxin

A proposed mechanism of action of ribonucleotide reductase is shown in Figure 22.15. Reduction of ribonucleotides requires electrons. These ultimately come from NADPH and are delivered to ribonucleotide reductase by either thioredoxin or glutaredoxin, as shown in Figure 22.16.

See also: Ribonucleotide Reductase and Deoxyribonucleotide Biosynthesis, Glutathione, Glutathione Reductase, Metabolism of Glutathione