Fumarate

Fumarate is an intermediate of the citric acid cycle and the glyoxylate cycle. produced by action of the enzyme succinate dehydrogenase on succinate. FADH 2 is produced from FAD in the reaction. Fumarate is converted to L-malate by addition of water to the molecule catalyzed by the enzyme fumarate hydratase.

See also: Enzymes of the Citric Acid Cycle, Intermediates of the citric acid cycle, Pathway of the citric acid cycle, Table 4.1, Succinate Dehydrogenase, Fumarate Hydratase

INTERNET LINKS:

> 1. Glyoxylate Cycle Metabolism

> 2. Citric Acid Cycle

> 3. Urea Cycle and Metabolism of Amino Groups