Pregnenolone

Pregnenolone is a steroid hormone that is the precursor of all the other major classes of steroid hormone. Pregnenolone is made from cholesterol by cleavage of part of the side chain after dual hydroxylation (see here). Subsequently pregnenolone is converted to progesterone (Figure 19.24) by dehydrogenation and double-bond isomerization.

See also: Steroid Metabolism, Steroid Hormones, Steroid Hormone Synthesis Cholesterol Biosynthesis, ,

INTERNET LINK: Steroid Hormone Metabolism