Erythromycin

Erythromycin is a polyketide antibiotic made via a modification of the fatty acid synthesis pathway in the bacterium Saccharopolyspora erythraea. It acts by binding to a specific site on the 23S rRNA and blocking elongation by interfering with the translocation step.

See also: Polyketides, Fatty Acid Biosynthesis, Antibiotic Inhibition of Translation, Elongation of Translation

INTERNET LINKS:

> 1. Polyketide Biosynthesis

> 2. 3D Model of Erythromycin (requires Chime)