dCMP Deaminase

dCMP deaminase is an enzyme in nucleotide biosynthesis that catalyzes the following reaction:

> dCMP + H 2O <=> dUMP + NH 3

The enzyme is activated by dCTP and inactivated by dTTP.

See also: Figure 22.17, Ribonucleotide Reductase and Deoxyribonucleotide Biosynthesis, Deoxyuridine Nucleotide Metabolism, Salvage Routes to Deoxyribonucleotide Synthesis, Nucleotide Analogs in Selection.