2',3'-Dideoxyinosine (ddI)

ddI is a drug used for the treatment of HIV infections. This nucleoside is anabolized to the corresponding 5' triphosphate, which acts as an inhibitor of viral reverse transcriptase in making DNA from the viral RNA.

Other inhibitors of reverse transcriptase are shown here.

See also: Salvage Routes to Deoxyribonucleotide Synthesis, Nucleotide Analogs in Medicine, Thymidine Kinase