Aspartic -Semialdehyde

Aspartic -semialdehyde (aspartate -semialdehyde) is an intermediate in aspartate metabolism (see here).

-Aspartyl Phosphate + NADPH + H+ <=> Aspartic Semialdehyde + NADP+ + Pi (catalyzed by Aspartate Semialdehyde Dehydrogenase)

Aspartic -Semialdehyde also participates in the reaction below that leads ultimately to lysine or to homoserine and methionine:

> Aspartic Semialdehyde + NADPH + H+ <=> Homoserine + NADP+ (catalyzed by Homoserine Dehydrogenase).

See also: Citric Acid Cycle Intermediates in Amino Acid Metabolism, Metabolism of Valine, Leucine, Isoleucine, and Lysine, Aspartate, Lysine, Homoserine, Methionine