Ketone Bodies

Ketone bodies are produced by the process of ketogenesis, which occurs when acetyl-CoA accumulates beyond its capacity to be oxidized or used for fatty acid synthesis. Under these conditions, the thiolase-catalyzed reaction favors production of acetoacetyl-CoA (Figure 18.21), which is ultimately converted to the ketone bodies - acetoacetate, acetone, and -hydroxybutyrate.

See also: Ketogenesis, Thiolase, Acetoacetate, Acetone, -Hydroxybutyrate, Biological Fuel, Brain Metabolism, Liver Metabolism

INTERNET LINK: Ketone Body Metabolism