L-Methylmalonyl-CoA Mutase

Methylmalonyl-CoA mutase catalyzes the conversion of L-methylmalonyl-coA to succinyl-CoA.

> L-Methylmalonyl-CoA <=> Succinyl-CoA

This reaction is important in the metabolism of propionyl-CoA, which arises from oxidation of odd-numbered chains of fatty acids.

Methylmalonyl-CoA mutase is an unusual vitamin B 12-containing enzyme.

See also: Oxidation of Odd-Numbered Fatty Acids, Propionyl-CoA, Vitamin B 12