Amylo-(1,4->1,6)-Transglycosylase (Branching Enzyme)

Branching enzyme is responsible in glycogen biosynthesis for making the many 1,6 branches characteristic of the glycogen molecules.

Deficiency of the enzyme causes the severe, and usually fatal, Andersen's disease (see here). Structure of glycogen in these individuals is abnormal - long chains of glucose with very few branches.

See also: Glycogen Metabolism Diseases, Glycogen Biosynthesis