L-3-Hydroxyacyl-S-CoA

L-3-Hydroxyacyl-S-CoA is an intermediate in fatty acid oxidation (Figure 18.16) that participates in the reactions below:

> 1. Trans-2-Enoyl-S-CoA + H 2O <=> L-3-Hydroxyacyl-S-CoA (catalyzed by Enoyl-CoA Hydratase)

> 2. L-3-Hydroxyacyl-S-CoA + NAD+ <=> 3-Ketoacyl-S-CoA + NADH + H+ (catalyzed by 3-Hydroxyacyl-CoA Dehydrogenase)

See also: -Oxidation of Saturated Fatty Acid, Unsaturated Fatty Acid Oxidation, Oxidation of Odd-Numbered Fatty Acids, Peroxisomal -Oxidation, Fatty Acids

INTERNET LINK: Fatty Acid Metabolism